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The incretin class — GLP-1, GLP-1/GIP, and triple agonists. Ranked roughly by potency in current trials. All require careful titration; see each protocol.

01
R
Retatrutide (GLP-3)
★★★★ 4/5 research
Protocol snapshot
Dose2 → 4 → 6 → 8 → 12 mg/week (titration ladder)
FrequencyOnce weekly subcutaneous
CycleStart at 2mg/week × 4 weeks → escalate by 2-4mg every 4 weeks → maintenance at 8-12mg/week
Full protocol + references →
🏆Our pick for Retatrutide (GLP-3)
Valor Peptides
20mg · USA · Card / Crypto
  • Third-party tested (Janoshik)
  • COAs provided — Comprehensive
  • Highest verification tier in stock
  • 4.8★ community rating
$200.34$167.41
$8.37/mg
Buy at Valor Peptides
Also solid
Modern Research Peptides
20mg · $9.52/mg
$190.49
Buy →
AMP Peptides
20mg · $5.73/mg
$114.68
Buy →
RetaOneLabs
20mg · $8.46/mg
$169.20
Buy →
02
T
Tirzepatide
★★★★★ 5/5 research
Protocol snapshot
Dose2.5 → 5 → 7.5 → 10 → 12.5 → 15 mg/week (FDA titration)
FrequencyOnce weekly subcutaneous
CycleStart 2.5mg/week × 4 weeks → escalate by 2.5mg every 4 weeks → maintenance at 10-15mg/week
Full protocol + references →
🏆Our pick for Tirzepatide
Modern Research Peptides
5mg · USA · Card / Crypto
  • Third-party tested (Janoshik)
  • COAs provided — Per-batch comprehensive
  • Highest verification tier in stock
  • 4.8★ community rating
Also solid
Peptidology
15mg · $12.69/mg
$190.36
Buy →
Ascension Peptides
10mg · $13.19/mg
$131.89
Buy →
AMP Peptides
10mg · $16.78/mg
$167.80
Buy →
03
S
Semaglutide
★★★★★ 5/5 research
Protocol snapshot
Dose0.25 → 0.5 → 1.0 → 1.7 → 2.4 mg/week (FDA titration)
FrequencyOnce weekly subcutaneous
CycleStart 0.25mg/week × 4 weeks → 0.5mg/week × 4 weeks → continue escalating monthly to 2.4mg/week target
Full protocol + references →
🏆Our pick for Semaglutide
Valor Peptides
5mg · USA · Card / Crypto
  • Third-party tested (Janoshik)
  • COAs provided — Comprehensive
  • Highest verification tier in stock
  • 4.8★ community rating
$107.94$81.04
$16.21/mg
Buy at Valor Peptides
Also solid
Modern Research Peptides
5mg · $24.19/mg
$120.93
Buy →
Peptidology
10mg · $22.28/mg
$222.77
Buy →
AMP Peptides
10mg · $11.03/mg
$110.28
Buy →
04
A
AOD-9604
★★★★★ 3/5 research
Protocol snapshot
Dose300-500 mcg/day
FrequencyOnce daily, AM on empty stomach
Cycle4-12 weeks continuous
Full protocol + references →
🏆Our pick for AOD-9604
Valor Peptides
10mg · USA · Card / Crypto
  • Third-party tested (Janoshik)
  • COAs provided — Comprehensive
  • Highest verification tier in stock
  • 4.8★ community rating
Also solid
Ascension Peptides
10mg · $9.90/mg
$98.96
Buy →
Double R Labs
10mg · $6.33/mg
$63.34
Buy →
RetaOneLabs
10mg · $6.76/mg
$67.63
Buy →

For research use only. Rankings reflect our source-verification methodology and current research maturity — not medical advice.